KLRC1 CLIA Kit for Human(Homo sapiens) | EIAab.comKLRC1 CLIA Kit for Human(Homo sapiens)

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KLRC1 (Gene name),

NKG2-A/NKG2-B type II integral membrane protein (Protein name ), NKG2A_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

KLRC1(NKG2A);

Protein name:

NKG2-A/NKG2-B type II integral membrane protein;

Alternative:

NK cell receptor A;CD159 antigen-like family member A;NKG2-A/B-activating NK receptor;

CD:

CD159a;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Can form disulfide-bonded heterodimer with CD94.

Function:

Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Subcellular Location:

Membrane Single-pass type II membrane protein

Protein Attributes:

Sequence length:

233

Sequence:

50:

100:

150:

200:

233:

SDNAELNCAV | LQVNRLKSAQ | CGSSIIYHCK | HKL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000352064

UniGene:

Hs.512576

Pfam:

PF00059

String:

P26715

MIM:

161555

KEGG:

hsa:3821

SMR:

P26715

Uniprot:

P26715

FOR

ELISA Kit for Human NKG2-A/NKG2-B type II integral membrane protein

Cat.:

E9020h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human NKG2-A/NKG2-B type II integral membrane protein

Cat.:

U9020h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human NKG2-A/NKG2-B type II integral membrane protein

Cat.:

P9020Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human NKG2-A/NKG2-B type II integral membrane protein

Protein for Human NKG2-A/NKG2-B type II integral membrane protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells."
Houchins J.P. , Yabe T. , McSherry C. , Bach F.H.
J. Exp. Med.173:1017-1020(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS NKG2-A AND NKG2-B);VARIANT SER-29
2.

"Genomic structure, chromosome location, and alternative splicing of the human NKG2A gene."
Plougastel B. , Jones T. , Trowsdale J.
Immunogenetics44:286-291(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS NKG2-A AND NKG2-B);VARIANT SER-29
3.

"Sequence analysis of a 62-kb region overlapping the human KLRC cluster of genes."
Plougastel B. , Trowsdale J.
Genomics49:193-199(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS NKG2-A AND NKG2-B);VARIANT SER-29
4.

"Identification and characterization of the NKG2A gene from large granular lymphocytic leukemia (LGL) cells."
Kothapalli R. , Kusmartseva I. , Loughran T.P. Jr.
Submitted (2001-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-29
5.

"The finished DNA sequence of human chromosome 12."
Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS NKG2-A AND NKG2-B);VARIANT SER-29
tissue: Blood.
tissue: Kidney.
7.

"The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition."
Sullivan L.C. , Clements C.S. , Beddoe T. , Johnson D. , Hoare H.L. , Lin J. , Huyton T. , Hopkins E.J. , Reid H.H. , Wilce M.C. , Kabat J. , Borrego F. , Coligan J.E. , Rossjohn J. , Brooks A.G.
Immunity27:900-911(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 113-232 IN COMPLEX WITH KLRD1;SUBUNIT;DISULFIDE BONDS
8.

"CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence."
Petrie E.J. , Clements C.S. , Lin J. , Sullivan L.C. , Johnson D. , Huyton T. , Heroux A. , Hoare H.L. , Beddoe T. , Reid H.H. , Wilce M.C. , Brooks A.G. , Rossjohn J.
J. Exp. Med.205:725-735(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF 113-232 IN COMPLEX WITH KLRD1;SUBUNIT;DISULFIDE BONDS
9.

"Structural basis for NKG2A/CD94 recognition of HLA-E."
Kaiser B.K. , Pizarro J.C. , Kerns J. , Strong R.K.
Proc. Natl. Acad. Sci. U.S.A.105:6696-6701(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (4.41 ANGSTROMS) OF 113-232 IN COMPLEX WITH KLRD1;SUBUNIT;DISULFIDE BONDS

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